Postdoctoral Fellow - Chaitali Ghosh Lab

The Chaitali Ghosh lab in the Department of Biomedical Engineering, Lerner Research Institute at Cleveland Clinic, Cleveland, OH is recruiting an enthusiastic and motivated postdoctoral research fellow to join on a project focusing on the Molecular Mechanism of Glucocorticoid Receptor, Cytochrome P450, and P-Glycoprotein Axis on Drug Regulation at the Blood-Brain Barrier in Epilepsy. The Ghosh laboratory is engaging in multi-disciplinary research projects in blood-brain barrier and epilepsy research by collaborating with basic and clinical researchers from Lerner Research Institute and the Neurological Institutes at Cleveland Clinic.

A successful postdoctoral candidate should have a PhD in the relevant field with a strong background in basic science, molecular biology, blood-brain barrier research, rodent seizure/epilepsy models and neuroscience. The candidate should be well-versed with basic neurobiology, molecular biology, cell culture techniques, rodent electrode implantation surgery and recording of brain activity. Applicant should be able to demonstrate a commitment to research, a collaborative work ethic and strong communication skills, both written and verbal. Highly motivated individuals with a PhD or MD/PhD in relevant area are encouraged to apply. Job Responsibilities includes independent project design with the goal of data generation, analysis, interpretation and manuscript preparation; perform experiments and make new discoveries; present data for manuscripts and conferences; procure independent funding to support research and train junior personnel.

Principal Investigator: Chaitali Ghosh, PhD

Lerner Research Institute Department: Biomedical Engineering

Lab Research Topics:

• Blood-brain barrier
• Epilepsy and epilepsy with other comorbidities
• Cellular and Molecular Neurobiology
• Pharmacokinetics and Pharmacodynamics
• Epigenetics and biomarkers
• For more information about the lab’s research, please visit: https://www.lerner.ccf.org/biomedical-engineering/ghosh/ or contact Dr. Chaitali Ghosh at ghoshc@ccf.org.

Job Responsibilities:

• Independent project design with the goal of data generation, analysis, interpretation and manuscript preparation
• Perform experiments independently
• Ability to design projects, generate, analyse and intergrate data for presentations and manuscript
• Procure independent funding to support research
• Rodent brain surgeries, electrode implantation & recording

Education:

• PhD or MD/PhD required
• MD with relevant laboratory experience may substitute for PhD

Languages:

• English Proficiency proof required for candidates arriving on J-1, J-2, or F1 + OPT visa status

Work Experience:

• Previous experience in a research or academic setting. Graduate student experience meets this requirement.
• Scientific writing experience

Additional Preferred Qualities:

• Passionate towards research and new discoveries
• Good communication skills and hardworking ethics
• Collegial and excellent team player
• Demonstrate good scientific writing skills and knowledge in basic research
• Ability to operate lab equipment's and computer software's for analysis

Physical Requirements:

• Ability to perform work in a stationary position for extended periods
• Ability to operate a computer and other office equipment
• Ability to communicate and exchange accurate information
• Ability to distinguish color
• Manual dexterity to handle specimens and repair equipment
• Ability to lift and transport equipment or specimens weighing up to 20 pounds
• May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment:

• PPE per institutional requirements; may vary by laboratory

Preferred Application Materials:

• CV or NIH format Biosketch,
• Statement of research accomplishments (1-page)
• Names of 3 Referees
• All application materials should be submitted directly via email to Chaitali Ghosh at ghoshc@ccf.org.

Keywords: Postdoc, Research, LRI, Lerner Research Institute, Research fellow, Cleveland Clinic, In vitro and In vivo Blood-brain barrier models, Rodent Brain surgery, Epilepsy Research, Blood-brain barrier Research, Rat and mouse models, Immunohistochemistry, Western Blotting, High Performance Liquid Chromatography/Mass Spectrometry, RT-PCR, Epigenetic, DNA methylation, ELISA, Primary cell cultures, Neurovascular Unit, Molecular Neurobiology, Biomarkers